ApoB optimal range and reference range
Compiled by Alina Radu, founder of Sera, from the published sources below · Last reviewed November 9, 2026
Sera's bands for ApoB:
- Optimal 0 – 70 mg/dL (0 – 0.7 g/L); sufficient 0 – 100 mg/dL (0 – 1 g/L); out of range above 100 mg/dL.
Evidence grade: Established clinical threshold. A band edge that corresponds to a recognised diagnostic, risk or treatment threshold from a major clinical guideline or public-health body.
All units
| Unit | Optimal | Sufficient | Out of range |
|---|---|---|---|
| mg/dL | 0 – 70 | 0 – 100 | above 100 |
| g/L | 0 – 0.7 | 0 – 1 | above 1 |
Bounded on the high side only — a low result is not treated as out of range. No evidence-based lower bound; treatment thresholds run as low as 60 mg/dL for people at very high risk.
What the evidence says
The optimal band ends at 70 mg/dL, the National Lipid Association's threshold for people at high cardiovascular risk. Thresholds differ by risk, from 60 to 90 mg/dL, and the association describes them as less well established than those for LDL. The acceptable band's upper edge of 100 mg/dL is wider than the association's 90 and has no source mapped to it yet. A low ApoB is not flagged.
Sources
- Role of apolipoprotein B in the clinical management of cardiovascular risk in adults: an Expert Clinical Consensus — National Lipid Association — Journal of Clinical Lipidology, 2024 · Professional societyProposes ApoB thresholds for considering more intensive treatment: 60 mg/dL at very high risk, 70 at high risk and 90 at borderline to intermediate risk. Sera's optimal band ends on the high-risk figure. The consensus notes these are less well established than the LDL thresholds they are derived from.
What Apolipoprotein B (ApoB) measures
A protein found on LDL, VLDL, and other particles that can clog arteries.
A better marker of heart risk than cholesterol numbers alone, because every artery-clogging particle carries one ApoB.